Pirenperone (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name, BANTooltip British Approved Name; developmental code names R-47456, R-50656) is a serotonin receptor antagonist described as an antipsychotic and tranquilizer which was never marketed. It is a relatively selective antagonist of the serotonin 5-HT2 receptors and has been used in scientific research to study the serotonin system. In the 1980s, the drug was found to block the effects of the lysergic acid diethylamide (LSD) in animals, and, along with ketanserin, led to the elucidation of the 5-HT2A receptor as the biological mediator of the effects of serotonergic psychedelics.

See also

  • Altanserin
  • Ketanserin
  • Setoperone
  • Risperidone
  • Ocaperidone

References


Wilde Pyrenäen Dokumentation & Reportage ARD Das Erste

Pyrenäen I Tag 3 Roses Espot Geführte Touren

Level of impulsivity was normalized after pirenperone treatment

Die Pyrenäen Schönheit mit Charakter Bergfreunde

Pirenperone treatment rescued the hyperactivity in the Fmr1 knockout